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Jan 15, - "Hairy" leukoplakia of the mouth is an unusual form of leukoplakia (caused by the Epstein-Barr virus) that is seen only in people who are infected with HIV, have AIDS, or AIDS-related complex. It consists of fuzzy, white patches on the tongue (hence, its name) and less frequently, elsewhere in the mouth. Sep 23, - White spots in the mouth and throat can be caused by a number of different conditions – here According to Dr Sindisiwe van Zyl who specialises in HIV and primary They can cover the tongue and the inside of the cheeks.